HEALthy Brain and Child Development (HBCD) Study

The HBCD Study is the largest longitudinal study of early brain and child development in the United States. This ambitious project will enroll over 7,000 participating families from across the United States and follow them from pregnancy through early childhood. Leading researchers in the fields of child development and neuroscience are working with participating families and their children to understand how the brain develops and is affected by exposure to substances and other environmental, social, and biological factors during pregnancy and after birth. What we learn from this research will have lasting impacts on future generations of children.

HBCD’s comprehensive protocol includes assessments of children’s physical, emotional, and cognitive development, plus surveys of parental health and well-being. The HBCD Study features wearable biosensors to calculate infant heartbeat and movement, biospecimen collection for genetic and epigenetic analyses and measurements of environmental and substance-use exposures, and multimodal neuroimaging and EEG across neurodevelopment. For more information about the HBCD Study, please visit the HBCD Study website.

The HBCD Study is supported by several Institutes, Centers, and Offices (ICOs) of the National Institutes of Health (NIH) as well as the NIH HEAL Initiative®. NIH ICOs include the:

National Institute on Drug Abuse
National Institute of Mental Health
National Cancer Institute
National Eye Institute
National Institute on Alcohol Abuse and Alcoholism
National Institute of Biomedical Imaging and Bioengineering
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Institute of Environmental Health Sciences
National Institute on Minority Health and Health Disparities
National Institute of Neurological Disorders and Stroke
NIH Office of Behavioral and Social Sciences Research
NIH Office of Research on Women’s Health

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Data Releases

Release 1.0

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Release 5.0 (DOI)

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Release 4.0 (DOI)

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Release 3.0 (DOI)

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